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Molecular networks in model systems.

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  • Institute for Systems Biology, Seattle, Washington 98103, USA. tgalitski@systemsbiology.org


Model organisms, especially the budding yeast, are leading systems in the transformation of biology into an information science. With the availability of genome sequences and genome-scale data generation technologies, the extraction of biological insight from complex integrated molecular networks has become a major area of research. Here I examine key concepts and review research developments. I propose specific areas of research effort to drive network analysis in directions that will promote modeling with increasing predictive power.

[PubMed - indexed for MEDLINE]
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