Nature. 2004 Oct 14;431(7010):760-7.

Computational roles for dopamine in behavioural control.

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Department of Neuroscience, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, USA. read@bcm.tmc.edu

Abstract

Neuromodulators such as dopamine have a central role in cognitive disorders. In the past decade, biological findings on dopamine function have been infused with concepts taken from computational theories of reinforcement learning. These more abstract approaches have now been applied to describe the biological algorithms at play in our brains when we form value judgements and make choices. The application of such quantitative models has opened up new fields, ripe for attack by young synthesizers and theoreticians.

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