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Genome Biol. 2004;5(10):243. Epub 2004 Sep 30.

Global nucleosome distribution and the regulation of transcription in yeast.

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  • 1Stowers Institute for Medical Research, 1,000 East 50th Street, Kansas City, MO 64110, USA.

Abstract

Recent studies show that active regulatory regions of the yeast genome have a lower density of nucleosomes than other regions, and that there is an inverse correlation between nucleosome density and the transcription rate of a gene. This may be the result of transcription factors displacing nucleosomes.

PMID:
15461807
[PubMed - indexed for MEDLINE]
PMCID:
PMC545588
Free PMC Article

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