Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Opt Lett. 2004 Sep 1;29(17):2016-8.

Spectral triangulation molecular contrast optical coherence tomography with indocyanine green as the contrast agent.

Author information

  • 1Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA. chyang@caltech.edu

Abstract

We report a new molecular contrast optical coherence tomography (MCOCT) implementation that profiles the contrast agent distribution in a sample by measuring the agent's spectral differential absorption. The method, spectra triangulation MCOCT, can effectively suppress contributions from spectrally dependent scatterings from the sample without a priori knowledge of the scattering properties. We demonstrate molecular imaging with this new MCOCT modality by mapping the distribution of indocyanine green, a FDA-approved infrared red dye, within a stage 54 Xenopus laevis.

PMID:
15455765
[PubMed - indexed for MEDLINE]
PMCID:
PMC1283115
Free PMC Article

Images from this publication.See all images (3)Free text

Fig. 1
Fig. 2
Fig. 3
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Optical Society of America Icon for PubMed Central
    Loading ...
    Write to the Help Desk