Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
J Pediatr Hematol Oncol. 2004 Oct;26(10):665-7.

Hyperexcitable blink reflex preceding the diagnosis of neuroblastoma.

Author information

  • 1Department of Psychiatry, Kansas University-Wichita, Wichita, Kansas, USA.


The diagnosis of neuroblastoma is sometimes preceded by development of a paraneoplastic syndrome, most commonly opsoclonus-myoclonus-ataxia (OMA). The authors describe a patient who developed a hyperexcitable blink reflex, without symptoms of OMA, prior to his oncologic diagnosis. The authors believe this may represent a distinct paraneoplastic process caused by increased dopaminergic stimulation of the blink reflex and suggest that children manifesting an unexplained hyperexcitable blink reflex should be screened for occult neuroblastoma.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Lippincott Williams & Wilkins
    Loading ...
    Write to the Help Desk