Curr Opin Microbiol. 2004 Oct;7(5):546-54.

The promise of functional genomics: completing the encyclopedia of a cell.

Hughes TR, Robinson MD, Mitsakakis N, Johnston M.

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Banting and Best Department of Medical Research, University of Toronto, 112 College St., Room 307, Toronto, ON, M5G 1L6, Canada. t.hughes@utoronto.ca

Abstract

Genome sequencing provides complete parts lists of organisms. This presents the obvious challenge of determining how each gene contributes to the life of the organism. This task seems increasingly feasible; however, progress to date suggests that increased interaction between systematic efforts and individual investigators will be critical to completing the encyclopedia of the yeast cell.

PMID:: 15451511; [PubMed - indexed for MEDLINE]

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