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Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage.
Hu J, McCall CM, Ohta T, Xiong Y.
Nat Cell Biol. 2004 Oct;6(10):1003-9. Epub 2004 Sep 26.
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Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis.
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