Hum Pathol. 1992 Jan;23(1):69-72.

Primary hepatic leiomyosarcoma in a child with the acquired immunodeficiency syndrome.

Ross JS, Del Rosario A, Bui HX, Sonbati H, Solis O.

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Department of Pathology and Laboratory Medicine, Albany Medical College, NY 12208.

Abstract

We report the first case of acquired immunodeficiency syndrome (AIDS)-related primary hepatic leiomyosarcoma in a 9-year-old girl. The pathologic diagnosis was made on a partial hepatectomy specimen and was confirmed by immunohistochemistry and electron microscopy. No human immunodeficiency virus-related nucleic acid was identified in tumor cells by in situ hybridization. Review of the AIDS-related literature reveals a rising incidence of tumors of smooth muscle origin in human immunodeficiency virus-infected patients. This case study details the eighth pediatric AIDS patient with a tumor of smooth muscle origin and represents the 20th and the youngest patient with primary hepatic leiomyosarcoma to be reported in the world literature.

PMID:: 1544673; [PubMed - indexed for MEDLINE]

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Cited by 4 PubMed Central articles

Primary hepatic leiomyosarcoma: Case report and literature review. [World J Gastrointest Oncol. 2011]
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AIDS-Related EBV-Associated Smooth Muscle Tumors: A Review of 64 Published Cases. [Patholog Res Int. 2011]
AIDS-Related EBV-Associated Smooth Muscle Tumors: A Review of 64 Published Cases.
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