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Curr Biol. 2004 Sep 21;14(18):R748-50.

Mitotic spindle: laser microsurgery in yeast cells.

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  • 1Department of Pediatric Oncology, Dana-Farber Cancer Institute and Division of Hematology/Oncology, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA.


Laser microsurgery has led to remarkable discoveries in a number of cell types. Two recent studies have shown that this classical technology can now be employed with small yeast cells. This advance will enable regional ablation to be combined with facile genetic manipulation in a eukaryotic cell.

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