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J Neuropsychiatry Clin Neurosci. 2004 Summer;16(3):295-305.

A pilot study of functional magnetic resonance imaging brain correlates of deception in healthy young men.

Author information

  • 1Center for Advanced Imaging Research, Department of Psychiatry, Medical University of South Carolina, South Carolina, USA. kozelfa@musc.edu

Abstract

We hypothesized that specific brain regions would activate during deception, and these areas would correlate with changes in electrodermal activity (EDA). Eight men were asked to find money hidden under various objects. While functional MRI images were acquired and EDA was recorded, the subjects gave both truthful and deceptive answers regarding the money's location. The group analysis revealed significant activation during deception in the orbitofrontal cortex (OFCx) and anterior cingulate (AC), but individual results were not consistent. Individually and as a group, EDA correlated with blood flow changes in the OFCx and AC. Specific brain regions were activated during deception, but the present technique lacks good predictive power for individuals.

PMID:
15377736
[PubMed - indexed for MEDLINE]
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