Format

Send to:

Choose Destination
See comment in PubMed Commons below
Cell. 2004 Sep 17;118(6):675-85.

Robustness of cellular functions.

Author information

  • 1Max Planck Institute for Dynamics of Complex Technical Systems, D-39106 Magdeburg, Germany. stelling@mpi-magdeburg.mpg.de

Abstract

Robustness, the ability to maintain performance in the face of perturbations and uncertainty, is a long-recognized key property of living systems. Owing to intimate links to cellular complexity, however, its molecular and cellular basis has only recently begun to be understood. Theoretical approaches to complex engineered systems can provide guidelines for investigating cellular robustness because biology and engineering employ a common set of basic mechanisms in different combinations. Robustness may be a key to understanding cellular complexity, elucidating design principles, and fostering closer interactions between experimentation and theory.

PMID:
15369668
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk