Br J Dermatol. 1992 Feb;126(2):179-84.

A controlled trial of traditional Chinese medicinal plants in widespread non-exudative atopic eczema.

Source

Department of Dermatology, Hospital for Sick Children, London, U.K.

Abstract

Severe and widespread atopic eczema often fails to respond adequately to currently available therapies. Following the observation of substantial benefit in patients receiving oral treatment with daily decoctions of traditional Chinese medicinal plants, we undertook a placebo-controlled double-blind trial of a specific prescription formulated for widespread non-exudative atopic eczema. Forty-seven children were given active treatment and placebo in random order, each for 8 weeks, with an intervening 4-week wash-out period. Thirty-seven children tolerated the treatment and completed the study. Response to active treatment was superior to response to placebo, and was clinically valuable. There was no evidence of haematological, renal or hepatic toxicity. These findings anticipate a wider therapeutic potential for traditional Chinese medicinal plants in this disease, and other skin diseases.

PMID:: 1536784; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Drugs, Chinese Herbal

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis. [Int J Dermatol. 1999]
A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis.
Fung AY, Look PC, Chong LY, But PP, Wong E. Int J Dermatol. 1999 May; 38(5):387-92.
One-year follow up of children treated with Chinese medicinal herbs for atopic eczema. [Br J Dermatol. 1994]
One-year follow up of children treated with Chinese medicinal herbs for atopic eczema.
Sheehan MP, Atherton DJ. Br J Dermatol. 1994 Apr; 130(4):488-93.
Efficacy and tolerability of a Chinese herbal medicine concoction for treatment of atopic dermatitis: a randomized, double-blind, placebo-controlled study. [Br J Dermatol. 2007]
Efficacy and tolerability of a Chinese herbal medicine concoction for treatment of atopic dermatitis: a randomized, double-blind, placebo-controlled study.
Hon KL, Leung TF, Ng PC, Lam MC, Kam WY, Wong KY, Lee KC, Sung YT, Cheng KF, Fok TF, et al. Br J Dermatol. 2007 Aug; 157(2):357-63. Epub 2007 May 14.
Review The efficacy of traditional Chinese herbal therapy in atopic eczema. [Int Arch Allergy Immunol. 1994]
Review The efficacy of traditional Chinese herbal therapy in atopic eczema.
Latchman Y, Whittle B, Rustin M, Atherton DJ, Brostoff J. Int Arch Allergy Immunol. 1994 Jul; 104(3):222-6.
Review Chinese herbal medicine for atopic eczema. [Cochrane Database Syst Rev. 2005]
Review Chinese herbal medicine for atopic eczema.
Zhang W, Leonard T, Bath-Hextall F, Chambers CA, Lee C, Humphreys R, Williams HC. Cochrane Database Syst Rev. 2005 Apr 18; (2):CD002291. Epub 2005 Apr 18.

See reviews... See all...

Cited by 14 PubMed Central articles

Chinese herbal medicine research in eczema treatment. [Chin Med. 2011]
Chinese herbal medicine research in eczema treatment.
Hon KL, Chan BC, Leung PC. Chin Med. 2011 Apr 28; 6:17. Epub 2011 Apr 28.
Unique aspects of herbal whole system research. [Explore (NY). 2009]
Unique aspects of herbal whole system research.
Zick SM, Schwabl H, Flower A, Chakraborty B, Hirschkorn K. Explore (NY). 2009 Mar-Apr; 5(2):97-103.
Study designs of randomized controlled trials not based on Chinese medicine theory are improper. [Chin Med. 2009]
Study designs of randomized controlled trials not based on Chinese medicine theory are improper.
Yan J, Engle VF, He Y, Jiao Y, Gu W. Chin Med. 2009 Feb 25; 4:3. Epub 2009 Feb 25.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

A controlled trial of traditional Chinese medicinal plants in widespread non-exu...
A controlled trial of traditional Chinese medicinal plants in widespread non-exudative atopic eczema.
Br J Dermatol. 1992 Feb ;126(2):179-84.

PubMed
Oestrogen deficiency and growth hormone treatment in childhood are not associate...
Oestrogen deficiency and growth hormone treatment in childhood are not associated with hearing in adults with turner syndrome.
Horm Res. 2004 ;62(4):182-6. Epub 2004 Sep 15 .

PubMed
Colophony (rosin) in newspapers may contribute to hand eczema.
Colophony (rosin) in newspapers may contribute to hand eczema.
Br J Dermatol. 1992 Feb ;126(2):161-5.

PubMed
Human RAS superfamily proteins and related GTPases.
Human RAS superfamily proteins and related GTPases.
Sci STKE. 2004 Sep 7 ;2004(250):RE13.

PubMed
GRIM-19, a cell death regulatory protein, is essential for assembly and function...
GRIM-19, a cell death regulatory protein, is essential for assembly and function of mitochondrial complex I.
Mol Cell Biol. 2004 Oct ;24(19):8447-56.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: