Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Nat Rev Mol Cell Biol. 2004 Aug;5(8):601-13.

Intermediate filaments mediate cytoskeletal crosstalk.

Author information

  • 1Feinberg School of Medicine, Northwestern University, Department of Cell and Molecular Biology, 303 East Chicago Avenue, Chicago, Illinois 60611, USA. l-chang1@northwestern.edu

Abstract

Intermediate filaments, actin-containing microfilaments and microtubules are the three main cytoskeletal systems of vertebrate and many invertebrate cells. Although these systems are composed of distinctly different proteins, they are in constant and intimate communication with one another. Understanding the molecular basis of this cytoskeletal crosstalk is essential for determining the mechanisms that underlie many cell-biological phenomena. Recent studies have revealed that intermediate filaments and their associated proteins are important components in mediating this crosstalk.

PMID:
15366704
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Nature Publishing Group
    Loading ...
    Write to the Help Desk