Acute fulminant subacute sclerosing panencephalitis with absent measles and PCR studies in cerebrospinal fluid

Brian H Y Chung; Patrick P K Ip; Virginia C N Wong; Janice Y C Lo; Brian Harding

doi:10.1016/j.pediatrneurol.2004.03.016

Acute fulminant subacute sclerosing panencephalitis with absent measles and PCR studies in cerebrospinal fluid

Pediatr Neurol. 2004 Sep;31(3):222-4. doi: 10.1016/j.pediatrneurol.2004.03.016.

Authors

Brian H Y Chung¹, Patrick P K Ip, Virginia C N Wong, Janice Y C Lo, Brian Harding

Affiliation

¹ Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, China.

PMID: 15351025
DOI: 10.1016/j.pediatrneurol.2004.03.016

Abstract

This report describes an atypical case of rapidly progressive subacute sclerosing panencephalitis presenting as transient visual agnosia and myoclonus in a 14-year-old male. There were no typical periodic complexes in serial electroencephalographic monitoring; cerebrospinal fluid measles antibody titer was negative. The diagnosis was made by molecular and histologic examination of open brain biopsy tissue.

Publication types

Case Reports

MeSH terms

Adolescent
Humans
Male
Measles / cerebrospinal fluid*
Measles / genetics
Polymerase Chain Reaction / methods*
Subacute Sclerosing Panencephalitis / cerebrospinal fluid*
Subacute Sclerosing Panencephalitis / genetics