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Bioinformatics. 2005 Feb 1;21(3):405-7. Epub 2004 Sep 3.

easyLINKAGE: a PERL script for easy and automated two-/multi-point linkage analyses.

Author information

  • 1Division of Nephrology, Department of Medicine, Medical University Clinic at the University of Würzburg, Würzburg, Germany. tom.linder@mail.uni-wuerzburg.de

Abstract

We have generated the program easyLINKAGE that combines automated setup and performance of linkage analyses and simulation under an easy to handle graphical user interface for Microsoft Windows 2000/XP and standard UNIX systems. The program package supports two-point linkage analyses (FastLink v4.1 and SPLink v1.09), multi-point linkage analyses [GENEHUNTER v2.1, GENEHUNTER-PLUS with the emendation by Kong and Cox v1.2 (allele sharing modelling)] and the simulation package SLINK v2.65, and provides genome-wide as well as chromosomal postscript plots of LOD scores, NPL scores, P-values and other parameters.

AVAILABILITY:

http://www.uni-wuerzburg.de/nephrologie/molecular_genetics/molecular_genetics.htm

SUPPLEMENTARY INFORMATION:

Supplementary information is available on the website.

PMID:
15347576
[PubMed - indexed for MEDLINE]
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