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Genome Biol. 2004;5(9):115. Epub 2004 Aug 31.

Predicting and validating microRNA targets.

Author information

  • 545 Life Sciences Addition, Department of Molecular and Cell Biology and Howard Hughes Medical Institute, University of California at Berkeley, Berkeley, CA 94720-3200, USA. lai@fruitfly.org

Abstract

Given that microRNAs select their targets by nucleotide base-pairing, it follows that it should be possible to find microRNA targets computationally. There has been considerable progress, but assessing success and biological significance requires a move into the 'wet' lab.

PMID:
15345038
[PubMed - indexed for MEDLINE]
PMCID:
PMC522861
Free PMC Article

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