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Pediatrics. 2004 Sep;114(3):782-5.

Intussusception in early childhood: a cohort study of 1.7 million children.

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  • 1Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS-A34, Atlanta, GA 30333, USA. thf7@cdc.gov



To describe incidence and temporal trends of intussusceptions in Danish children during 1980 to 2001.


A population-based cohort study was conducted of 1.67 million children who were younger than 5 years during 1980 to 2001 and were followed up for 6.66 million person-years. The Danish National Patient Registry was used to identify cases of intussusception in the cohort. Age-specific incidence rates were main outcome measure.


A total of 1814 cases of intussusception among children who were younger than 5 years were reported from 1980 to 2001. The incidence rate remained fairly constant during 1980 to 1990 but decreased by 55% (95% confidence interval: 43%-65%) from 1990 to 2001. The reduction was most pronounced among children aged 3 to 5 months.


The incidence of intussusception among Danish children declined significantly during the 1990s, particularly among infants 3 to 5 months of age.

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