Trends Biochem Sci. 1992 Apr;17(4):135-40.

NF-kappa B and related proteins: Rel/dorsal homologies meet ankyrin-like repeats.

Source

Unité de Biologie Moléculaire du Gène, U. 277 INSERM, Institut Pasteur, Paris, France.

Abstract

Molecular cloning of the subunits of the transcription factor NF-kappa B and its inhibitor l kappa B revealed regions of sequence homology with two different classes of proteins: the Rel/dorsal family and a heterogeneous group of proteins containing ankyrin-like repeats. Both the Rel/dorsal homology domain and the ankyrin-like repeats appear to play important roles in protein-protein interactions that regulate localization and activity of the NF-kappa B subunits.

PMID:: 1533967; [PubMed - indexed for MEDLINE]

Supplemental Content

Save items

Related citations in PubMed

The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding. [Proc Natl Acad Sci U S A. 1992]
The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding.
Hatada EN, Nieters A, Wulczyn FG, Naumann M, Meyer R, Nucifora G, McKeithan TW, Scheidereit C. Proc Natl Acad Sci U S A. 1992 Mar 15; 89(6):2489-93.
Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity. [Proc Natl Acad Sci U S A. 1992]
Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity.
Inoue J, Kerr LD, Rashid D, Davis N, Bose HR Jr, Verma IM. Proc Natl Acad Sci U S A. 1992 May 15; 89(10):4333-7.
Review The inhibitory ankyrin and activator Rel proteins. [Curr Opin Genet Dev. 1992]
Review The inhibitory ankyrin and activator Rel proteins.
Nolan GP, Baltimore D. Curr Opin Genet Dev. 1992 Apr; 2(2):211-20.
A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site. [Mol Cell Biol. 1992]
A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site.
Bours V, Burd PR, Brown K, Villalobos J, Park S, Ryseck RP, Bravo R, Kelly K, Siebenlist U. Mol Cell Biol. 1992 Feb; 12(2):685-95.
Review Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system. [Curr Opin Cell Biol. 1993]
Review Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system.
Liou HC, Baltimore D. Curr Opin Cell Biol. 1993 Jun; 5(3):477-87.

See reviews... See all...

Cited by over 100 PubMed Central articles

NFκB1 and NFκBIA polymorphisms are associated with increased risk for sporadic colorectal cancer in a southern Chinese population. [PLoS One. 2011]
NFκB1 and NFκBIA polymorphisms are associated with increased risk for sporadic colorectal cancer in a southern Chinese population.
Song S, Chen D, Lu J, Liao J, Luo Y, Yang Z, Fu X, Fan X, Wei Y, Yang L, et al. PLoS One. 2011; 6(6):e21726. Epub 2011 Jun 30.
Review Structural studies of NF-κB signaling. [Cell Res. 2011]
Review Structural studies of NF-κB signaling.
Zheng C, Yin Q, Wu H. Cell Res. 2011 Jan; 21(1):183-95. Epub 2010 Dec 7.
Notch signaling and neurogenesis in normal and stroke brain. [Int J Physiol Pathophysiol Pha...]
Notch signaling and neurogenesis in normal and stroke brain.
Xiao MJ, Han Z, Shao B, Jin K. Int J Physiol Pathophysiol Pharmacol. 2009; 1(2):192-202. Epub 2009 Nov 10.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

NF-kappa B and related proteins: Rel/dorsal homologies meet ankyrin-like repeats...
NF-kappa B and related proteins: Rel/dorsal homologies meet ankyrin-like repeats.
Trends Biochem Sci. 1992 Apr ;17(4):135-40.

PubMed
Self-renewal, multipotency, and the existence of two cell populations within an ...
Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche.
Cell. 2004 Sep 3 ;118(5):635-48.

PubMed
Comparative utility of instruments for monitoring sleepiness-related performance...
Comparative utility of instruments for monitoring sleepiness-related performance decrements in the operational environment.
J Sleep Res. 2004 Sep ;13(3):219-27.

PubMed
Virtual screening in lead discovery and optimization.
Virtual screening in lead discovery and optimization.
Curr Opin Drug Discov Devel. 2004 Jul ;7(4):396-403.

PubMed
Functional diversity of E1A gene autoregulation among human adenoviruses.
Functional diversity of E1A gene autoregulation among human adenoviruses.
J Virol. 1992 Jun ;66(6):3833-45.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

NF-kappa B and related proteins: Rel/dorsal homologies meet ankyrin-like repeats.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

Supplemental Content

Save items

Related citations in PubMed

Cited by over 100 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information