Clozapine treatment of schizophrenia: implications for forensic psychiatry

J Clin Forensic Med. 1995 Mar;2(1):9-16. doi: 10.1016/1353-1131(95)90034-9.

Abstract

Clozapine, a new antipsychotic medication, is now the first-line treatment for neuroleptic refractory schizophrenia. Preliminary observations on its efficacy in treating schizophrenic patients with co-morbid substance abuse and, particularly, schizophrenic patients with persistent aggressive behaviour suggests that clozapine may provide a useful treatment option in forensic patient populations. Potential applications of clozapine and management considerations that are relevant to the forensic setting are discussed.