Bioessays. 1992 Feb;14(2):89-95.

The rel family of proteins.

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Department of Cell and Developmental Biology, Roche Research Center, Nutley, New Jersey 07110.

Abstract

The rel family of proteins can be defined as a group of proteins that share sequence homology over a 300 amino acid region termed the rel domain. The rel family comprises important regulatory proteins from a wide variety of species and includes the Drosophila morphogen dorsal, the mammalian transcription factor NF-kappa B, the avian oncogene v-rel, and the cellular proto-oncogene c-rel. Over the last two years it has become apparent that these proteins function as DNA-binding transcription factors, and that their activity is regulated at the level of subcellular localization.

PMID:: 1533515; [PubMed - indexed for MEDLINE]

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Differential pp40I kappa B-beta inhibition of DNA binding by rel proteins. [Mol Cell Biol. 1993]
Differential pp40I kappa B-beta inhibition of DNA binding by rel proteins.
Diehl JA, McKinsey TA, Hannink M. Mol Cell Biol. 1993 Mar; 13(3):1769-78.
A yeast transcription assay defines distinct rel and dorsal DNA recognition sequences. [New Biol. 1991]
A yeast transcription assay defines distinct rel and dorsal DNA recognition sequences.
Kamens J, Brent R. New Biol. 1991 Oct; 3(10):1005-13.
Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal. [Cell. 1990]
Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal.
Ghosh S, Gifford AM, Riviere LR, Tempst P, Nolan GP, Baltimore D. Cell. 1990 Sep 7; 62(5):1019-29.
Review The Ets family of transcription factors. [Eur J Biochem. 1993]
Review The Ets family of transcription factors.
Wasylyk B, Hahn SL, Giovane A. Eur J Biochem. 1993 Jan 15; 211(1-2):7-18.
Review Molecular analysis of the ets genes and their products. [Crit Rev Oncog. 1990]
Review Molecular analysis of the ets genes and their products.
Watson DK, Ascione R, Papas TS. Crit Rev Oncog. 1990; 1(4):409-36.

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Cited by 11 PubMed Central articles

Role of sequence encoded κB DNA geometry in gene regulation by Dorsal. [Nucleic Acids Res. 2011]
Role of sequence encoded κB DNA geometry in gene regulation by Dorsal.
Mrinal N, Tomar A, Nagaraju J. Nucleic Acids Res. 2011 Dec; 39(22):9574-91. Epub 2011 Sep 2.
Embryonic lethality in mice lacking the nuclear factor of activated T cells 5 protein due to impaired cardiac development and function. [PLoS One. 2011]
Embryonic lethality in mice lacking the nuclear factor of activated T cells 5 protein due to impaired cardiac development and function.
Mak MC, Lam KM, Chan PK, Lau YB, Tang WH, Yeung PK, Ko BC, Chung SM, Chung SK. PLoS One. 2011; 6(7):e19186. Epub 2011 Jul 12.
Dynamic repositioning of dorsal to two different kappaB motifs controls its autoregulation during immune response in Drosophila. [J Biol Chem. 2010]
Dynamic repositioning of dorsal to two different kappaB motifs controls its autoregulation during immune response in Drosophila.
Mrinal N, Nagaraju J. J Biol Chem. 2010 Jul 30; 285(31):24206-16. Epub 2010 May 26.

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