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    Pediatr Neurol. 1992 Jan-Feb;8(1):72-4.

    Globus pallidus calcification in Down syndrome with progressive neurologic deficits.

    Source

    Department of Pediatrics, Kyoto Prefectural University of Medicine, Japan.

    Abstract

    We report a 10-year-old Down syndrome patient who developed dystonia, choreoathetosis, dysarthria, and dysphagia beginning with hemiparesis. Cranial computed tomography disclosed bilateral calcification in the globus pallidus which resembled a sign of premature aging. Conversely, the clinical course and magnetic resonance imaging findings resembled those of Hallervorden-Spatz syndrome.

    PMID:
    1532715
    [PubMed - indexed for MEDLINE]

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