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1: Cancer. 2004 Sep 15;101(6):1338-44.Click here to read Links

Adjuvant postoperative radiotherapy for colon carcinoma.

Mendenhall WM, Amos EH, Rout WR, Zlotecki RA, Hochwald SN, Cance WG.

Department of Radiation Oncology, University of Florida College of Medicine, Gainesville 32610, USA. mendewil@shands.ufl.edu

BACKGROUND: The objective of this report was to review the role of adjuvant postoperative radiotherapy (RT) for patients with adenocarcinoma of the colon. METHODS: The authors reviewed the pertinent literature. RESULTS: Data suggested that locoregional postoperative RT improves both local control and survival for patients with T4N0-N1 tumors. There also may be a benefit for patients with T3N1-N2 tumors, but the data were equivocal. Whole abdominal RT may result in a similar benefit but is associated with increased toxicity. CONCLUSIONS: Postoperative RT should be considered for patients with T4N0-N1 colon carcinoma. Locoregional fields should be used. Copyright 2004 American Cancer Society.

PMID: 15316945 [PubMed - indexed for MEDLINE]