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    Biochemistry (Mosc). 2004 Jul;69(7):738-41.

    Mechanisms of neuroprotective action of vitamin D(3).

    Kalueff AV, Eremin KO, Tuohimaa P.

    Center of Physiology and Biochemical Research, Kiev 01042, Ukraine. cpbr@mail.ru

    This review considers modern data on the mechanisms underlying the neuroprotective effect of the neurosteroid vitamin D(3) and its receptors in the nervous system. Special attention is paid to Ca2+ regulation, stimulation of neurotrophin release, interaction with reactive oxygen and nitrogen species, and neuroimmunomodulatory effects of calcitriol, the main biologically active form of vitamin D(3), in the nervous system.

    PMID: 15310271 [PubMed - indexed for MEDLINE]

    Supplemental Content

    Patient drug information

    • Calcitriol (Rocaltrol®)

      Calcitriol is a form of vitamin D that is used to treat and prevent low levels of calcium in the blood of patients whose kidneys or parathyroid glands (glands in the neck that release natural substances to control the am...