Pharmacopsychiatry. 1992 Jul;25(4):187-91.

Bipolar illness, lithium prophylaxis, and pregnancy.

Source

Willem Arntsz Huis, Utrecht, The Netherlands.

Abstract

In advising bipolar patients wishing to become pregnant, Weinstein's guidelines were extended to seven stages: contraceptive measures; genetic counseling; discontinuing lithium in the first trimester or prescribing alternatives; ultrasound scanning for congenital anomalies, low lithium levels during pregnancy; discontinuing lithium at the end of pregnancy; starting immediately after birth, no breast feeding, observation of the neonate in the neonatal ward; and close observation of the patient in the follow-up year. Of the 15 bipolar patients, 11 gave birth to healthy children (five of them twice). Most patients knew nothing about the inheritance of bipolar illness. Four made no further attempt to become pregnant: two in view of a serious possibility of inheritance, the other two after a severe relapse. Three patients chose an alternative to lithium medication (carbamazepine and haloperidol). Postpartum, 27% of the patients who used medication relapsed and 60% of the patients who used none relapsed.

PMID:: 1528958; [PubMed - indexed for MEDLINE]

MeSH Terms, Substances

MeSH Terms

Substances

Lithium

LinkOut - more resources

Full Text Sources

Medical

Molecular Biology Databases

LITHIUM, ELEMENTAL - HSDB

Supplemental Content

Save items

Related citations in PubMed

Prescribing lithium for pregnant women. [Am J Psychiatry. 1988]
Prescribing lithium for pregnant women.
Cohen LS, Rosenbaum JF, Heller VL. Am J Psychiatry. 1988 Jun; 145(6):772-3.
Risk of recurrence of bipolar disorder in pregnant and nonpregnant women after discontinuing lithium maintenance. [Am J Psychiatry. 2000]
Risk of recurrence of bipolar disorder in pregnant and nonpregnant women after discontinuing lithium maintenance.
Viguera AC, Nonacs R, Cohen LS, Tondo L, Murray A, Baldessarini RJ. Am J Psychiatry. 2000 Feb; 157(2):179-84.
[Treatment of bipolar disorder during pregnancy and puerperium period. A case report]. [Rev Med Chil. 2001]
[Treatment of bipolar disorder during pregnancy and puerperium period. A case report].
Retamal P, Cantillano V. Rev Med Chil. 2001 May; 129(5):556-60.
Review The use of lithium and management of women with bipolar disorder during pregnancy and lactation. [J Clin Psychiatry. 1998]
Review The use of lithium and management of women with bipolar disorder during pregnancy and lactation.
Llewellyn A, Stowe ZN, Strader JR Jr. J Clin Psychiatry. 1998; 59 Suppl 6:57-64; discussion 65.
Review Family planning for women with bipolar disorder. [Hosp Community Psychiatry. 1992]
Review Family planning for women with bipolar disorder.
Packer S. Hosp Community Psychiatry. 1992 May; 43(5):479-82.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Bipolar illness, lithium prophylaxis, and pregnancy.
Bipolar illness, lithium prophylaxis, and pregnancy.
Pharmacopsychiatry. 1992 Jul ;25(4):187-91.

PubMed
Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa ...
Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis.
Microbiology. 2004 Aug ;150(Pt 8):2669-76.

PubMed
Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-pr...
Mesothelin-specific CD8(+) T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients.
J Exp Med. 2004 Aug 2 ;200(3):297-306.

PubMed
Prospective, multicenter, randomized phase II trial of the herbal supplement, PC...
Prospective, multicenter, randomized phase II trial of the herbal supplement, PC-SPES, and diethylstilbestrol in patients with androgen-independent prostate cancer.
J Clin Oncol. 2004 Sep 15 ;22(18):3705-12. Epub 2004 Aug 2 .

PubMed
Stress-induced DNA duplex destabilization (SIDD) in the E. coli genome: SIDD sit...
Stress-induced DNA duplex destabilization (SIDD) in the E. coli genome: SIDD sites are closely associated with promoters.
Genome Res. 2004 Aug ;14(8):1575-84.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: