Abstract
N6-Protected adenosines have been prepared from inosines by activation of the C6 position and Pd-catalyzed coupling with amides. An efficient route to [6-15NH2]-N6-benzoyladenosine and [1-15N,6-15NH2]-N6-benzoyladenosine has been achieved.
Copyright 2004 American Chemical Society
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenosine / analogs & derivatives*
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Adenosine / chemical synthesis*
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Amides / chemistry
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Catalysis
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Indicators and Reagents
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Inosine / chemistry*
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Nitrogen Isotopes
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Palladium / chemistry*
Substances
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Amides
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Indicators and Reagents
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Nitrogen Isotopes
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Inosine
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Palladium
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Adenosine