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Aust N Z J Obstet Gynaecol. 2004 Aug;44(4):298-301.

Effects of coasting on the outcome of intracytoplasmic sperm injection-embryo transfer cycles.

Author information

  • 1IVF Department, Ozel Ege Tup Bebek Merkezi, Izmir, Turkey. sebnem.aktan@deu.edu.tr

Abstract

OBJECTIVES:

To determine the effects of 'coasting' on the outcome of controlled ovarian hyperstimulation (COH) and intracytoplasmic sperm injection-embryo transfer (ICSI-ET).

DESIGN:

Retrospective study.

SETTING:

IVF Centre, Ozel Ege Tup Bebek Merkezi, Izmir, Turkey.

SAMPLE:

Twenty-six coasted and 52 non-coasted COH and ICSI-ET patients were enrolled in this retrospective study.

METHODS:

Coasted patients were enrolled consecutively during the study period, and two non-coasted controls were selected from our database for each coasted patient. Coasting was decided when serum oestradiol level was > or = 4000 pg/mL. Groups were compared using chi2 and Mann-Whitney U-tests for statistical analysis.

MAIN OUTCOME MEASURES:

Number of oocytes collected, metaphase II (MII) oocytes and cleaving embryos, the fertilisation rate and clinical pregnancy rate were the main outcome measures.

RESULTS:

Number of oocytes collected, number of MII oocytes, number of cleaving embryos, fertilisation rate and clinical pregnancy rate for the coasted and non-coasted groups were 15.5 +/- 5.2 and 14.0 +/- 7.1, 9.7 +/- 4.8 and 9.3 +/- 3.9, 6.8 +/- 3.9 and 5.8 +/- 3.1, 0.85 +/- 0.18 and 0.78 +/- 0.18, 13/26 and 24/52, respectively; these differences were not statistically significant. None of the patients in the coasted group were hospitalised for signs or findings of severe ovarian hyperstimulation syndrome.

CONCLUSIONS:

Coasting does not adversely affect the number and the function of mature oocytes and the clinical pregnancy rate.

PMID:
15281999
[PubMed - indexed for MEDLINE]
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