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Nat Med. 2004 Jul;10 Suppl:S58-62.

Genetic clues to the pathogenesis of Parkinson's disease.

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  • 1Department of Neurology, Center for Neurobiology and Behavior, Columbia University, New York, New York 10032, USA.


Recent years have seen an explosion in the rate of discovery of genetic defects linked to Parkinson's disease. These breakthroughs have not provided a direct explanation for the disease process. Nevertheless, they have helped transform Parkinson's disease research by providing tangible clues to the neurobiology of the disorder.

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