Format

Send to:

Choose Destination
See comment in PubMed Commons below
Bioinformatics. 2004 Dec 12;20(18):3673-5. Epub 2004 Jul 22.

SelSim: a program to simulate population genetic data with natural selection and recombination.

Author information

  • 1Department of Statistics, 1 South Parks Road, Oxford OX1 3TG, UK. spencer@stats.ox.ac.uk <spencer@stats.ox.ac.uk>

Abstract

SelSim is a program for Monte Carlo simulation of DNA polymorphism data for a recombining region within which a single bi-allelic site has experienced natural selection. SelSim allows simulation from either a fully stochastic model of, or deterministic approximations to, natural selection within a coalescent framework. A number of different mutation models are available for simulating surrounding neutral variation. The package enables a detailed exploration of the effects of different models and strengths of selection on patterns of diversity. This provides a tool for the statistical analysis of both empirical data and methods designed to detect natural selection.

AVAILABILITY:

http://www.stats.ox.ac.uk/mathgen/software.html.

SUPPLEMENTARY INFORMATION:

http://www.stats.ox.ac.uk/mathgen/software.html.

PMID:
15271777
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk