Curr Biol. 2004 Jul 27;14(14):R575-7.

Comparative genomics: prediction of the ciliary and basal body proteome.

Source

Program in Molecular Medicine, University of Massachusetts Medical School, Biotech II, Suite 213, 373 Plantation St., Worcester, Massachusetts 01605, USA. gregory.pazour@umassmed.edu

Abstract

Defects in mammalian cilia lead to a range of diseases, but our understanding of the composition of these organelles and of the basal bodies from which they arise is limited. Two recent studies used comparative genomics to predict the ciliary and basal body proteomes, providing datasets that are rich sources of human disease gene candidates.

Comment in

Curr Biol. 2004 Nov 9;14(21):R913-4.

PMID:: 15268880; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Review

MeSH Terms

Substances

Proteome

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Save items

Related citations in PubMed

Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene. [Cell. 2004]
Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene.
Li JB, Gerdes JM, Haycraft CJ, Fan Y, Teslovich TM, May-Simera H, Li H, Blacque OE, Li L, Leitch CC, et al. Cell. 2004 May 14; 117(4):541-52.
Review Cilia and flagella revealed: from flagellar assembly in Chlamydomonas to human obesity disorders. [Cell. 2004]
Review Cilia and flagella revealed: from flagellar assembly in Chlamydomonas to human obesity disorders.
Snell WJ, Pan J, Wang Q. Cell. 2004 Jun 11; 117(6):693-7.
Cilia: tails of the unexpected. [Nature. 2007]
Cilia: tails of the unexpected.
Ainsworth C. Nature. 2007 Aug 9; 448(7154):638-41.
Review Cilium-generated signaling and cilia-related disorders. [Lab Invest. 2005]
Review Cilium-generated signaling and cilia-related disorders.
Pan J, Wang Q, Snell WJ. Lab Invest. 2005 Apr; 85(4):452-63.
Review Lifting the lid on Pandora's box: the Bardet-Biedl syndrome. [Curr Opin Genet Dev. 2005]
Review Lifting the lid on Pandora's box: the Bardet-Biedl syndrome.
Beales PL. Curr Opin Genet Dev. 2005 Jun; 15(3):315-23.

See reviews... See all...

Cited by 5 PubMed Central articles

Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation. [BMC Dev Biol. 2010]
Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation.
DeRouen MC, Zhen H, Tan SH, Williams S, Marinkovich MP, Oro AE. BMC Dev Biol. 2010 Nov 10; 10:112. Epub 2010 Nov 10.
Bug22p, a conserved centrosomal/ciliary protein also present in higher plants, is required for an effective ciliary stroke in Paramecium. [Eukaryot Cell. 2010]
Bug22p, a conserved centrosomal/ciliary protein also present in higher plants, is required for an effective ciliary stroke in Paramecium.
Laligné C, Klotz C, de Loubresse NG, Lemullois M, Hori M, Laurent FX, Papon JF, Louis B, Cohen J, Koll F. Eukaryot Cell. 2010 Apr; 9(4):645-55. Epub 2010 Jan 29.
Review The primary cilium as a complex signaling center. [Curr Biol. 2009]
Review The primary cilium as a complex signaling center.
Berbari NF, O'Connor AK, Haycraft CJ, Yoder BK. Curr Biol. 2009 Jul 14; 19(13):R526-35.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Comparative genomics: prediction of the ciliary and basal body proteome.
Comparative genomics: prediction of the ciliary and basal body proteome.
Curr Biol. 2004 Jul 27 ;14(14):R575-7.

PubMed
Nutritional value of milk and meat products derived from cloning.
Nutritional value of milk and meat products derived from cloning.
Cloning Stem Cells. 2004 ;6(2):172-7.

PubMed
Stress responses and innate immunity: aging as a contributory factor.
Stress responses and innate immunity: aging as a contributory factor.
Aging Cell. 2004 Aug ;3(4):151-60.

PubMed
Beyond medicalization-healthicization? A rejoinder to Hislop and Arber.
Beyond medicalization-healthicization? A rejoinder to Hislop and Arber.
Sociol Health Illn. 2004 May ;26(4):453-9; discussion 460-3.

PubMed
Current-dependent extension of the Perdew-Burke-Ernzerhof exchange-correlation f...
Current-dependent extension of the Perdew-Burke-Ernzerhof exchange-correlation functional.
J Chem Phys. 2004 Feb 1 ;120(5):2105-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: