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Curr Biol. 2004 Jul 27;14(14):R565-7.

Telomerase RNA: a flexible RNA scaffold for telomerase biosynthesis.

Author information

  • 1Department of Biochemistry, Tulane University Heath Sciences Center, New Orleans, Louisiana 70112, USA. alustig@tulane.edu

Abstract

Determination of the structure of the yeast telomerase RNA component TLC1 has been hampered by its large size and high rate of evolutionary divergence. But detailed phylogenetic comparisons have now revealed the unusually flexible and modular architecture of this important RNA molecule.

PMID:
15268876
[PubMed - indexed for MEDLINE]
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