Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Pediatr Neurol. 2004 Jul;31(1):52-5.

Clinical predictors for outcome in infants with epilepsy.

Author information

  • 1Department of Paediatric Neurology, University Hospitals KULeuven, Herestraat 49, B3000 Leuven, Belgium.

Abstract

In this prospective study, the clinical parameters predictive for the outcome in infants with onset of epilepsy below 12 months of age (n = 60) were determined. At the end of the follow-up period, patients were included in a symptomatic or idiopathic group. In approximately 60% of all children, epilepsy could be controlled with standard antiepileptic monotherapy. The epilepsy was more difficult to control in the symptomatic group, reflected by the larger number of drug switches during follow-up. Seizure outcome was not influenced by age of onset, type of seizures, or electroencephalographic abnormalities at the epilepsy onset. Developmental outcome was significantly worse in the symptomatic group. In the idiopathic group, the control of epilepsy was the major developmental outcome factor, indicating a possible deleterious effect of seizures on brain development in that group.

PMID:
15246493
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk