Your browser version may not work well with NCBI's Web applications. More information here...
1: Clin Exp Dermatol. 2004 Jul;29(4):360-2.Click here to read Links

Scleroderma and the taxanes. Is there really a link?

Farrant PB, Mortimer PS, Gore M.

Department of Dermatology, St George's Hospital, The Royal Marsden Hospital, London, UK. drpaulfarrant@doctors.org.uk

Scleroderma has been associated with exposure to many substances in the past ranging from vinyl chloride to silicon dioxide. In recent years there have been a number of case reports linking modern chemotherapy agents, such as the taxanes to the development of scleroderma like changes. We present a further case of scleroderma in association with chemotherapy but question the role of some of the agents previously implicated. A brief review of the current literature is included.

PMID: 15245529 [PubMed - indexed for MEDLINE]