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Scleroderma and the taxanes. Is there really a link?
Department of Dermatology, St George's Hospital, The Royal Marsden Hospital, London, UK. drpaulfarrant@doctors.org.uk
Scleroderma has been associated with exposure to many substances in the past ranging from vinyl chloride to silicon dioxide. In recent years there have been a number of case reports linking modern chemotherapy agents, such as the taxanes to the development of scleroderma like changes. We present a further case of scleroderma in association with chemotherapy but question the role of some of the agents previously implicated. A brief review of the current literature is included.
PMID: 15245529 [PubMed - indexed for MEDLINE]
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