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Exerc Sport Sci Rev. 2004 Jul;32(3):120-6.

Novel aspects of skeletal muscle glycogen and its regulation during rest and exercise.

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  • 1Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.


Although it is often viewed as a homogenous substrate, glycogen is comprised of individual granules or 'glycosomes' that vary in their composition, subcellular localization, and metabolism. These differences result in additional levels of regulation allowing granules to be regulated individually or regionally within the cell during both rest and exercise.

Copyright 2004 American College of Sports Medicine

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