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Curr Opin Investig Drugs. 2004 Jun;5(6):657-67.

Epothilone D (Kosan/Roche).

Author information

  • 1Department of Molecular Biology and Functional Genomics, Stockholm University, SE-106 91 Stockholm, Sweden. ada.kolman@molbio.su.se

Abstract

Kosan and Roche are developing the microtubule inhibitor epothilone D (KOS-862 and NSC-703147), an analog of epothilone B for the potential treatment of cancer. Phase II trials in colorectal, metastatic breast and non-small-cell lung cancers were initiated in December 2003.

PMID:
15242255
[PubMed - indexed for MEDLINE]
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