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Sci STKE. 2004 Jun 29;2004(240):tr6.

Teaching resource. Beta-catenin signaling and axis specification.

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  • 1Howard Hughes Medical Institute and Department of Pharmacology, University of Washington School of Medicine, Seattle, WA 98195, USA.


This animation provides a representation of the beta-catenin signaling pathway in response to fertilization and the process of axis specification that occurs early in development. The process shown is based on analysis of embryos of the amphibian Xenopus. This animation would be useful in illustrating events that occur early in embryogenesis and how embryos become polarized as a consequence of localized signaling processes.

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