Experimental determination of compound action potential direction and propagation velocity from multi-electrode nerve cuffs

Med Eng Phys. 2004 Jul;26(6):531-4. doi: 10.1016/j.medengphy.2004.02.002.

Abstract

Information extracted from whole-nerve electroneurograms, recorded using electrode cuffs, can provide signals to neuroprostheses. However, the amount of information that can be extracted from a single tripole is limited. This communication demonstrates how previously unavailable information about the direction of action potential propagation and velocity can be obtained using a multi-electrode cuff and that the arrangement acts as a velocity-selective filter. Results from in vitro experiments on frog nerves are presented.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Action Potentials / physiology*
  • Algorithms*
  • Amplifiers, Electronic
  • Animals
  • Diagnosis, Computer-Assisted / methods*
  • Electrodes, Implanted*
  • Equipment Design
  • Equipment Failure Analysis
  • Feasibility Studies
  • Microelectrodes*
  • Neural Conduction / physiology*
  • Ranidae
  • Sciatic Nerve / physiology*