Bull Exp Biol Med. 2004 Mar;137(3):249-51.

Comparison of antioxidants in the ability to prevent cataract in prematurely aging OXYS rats.

Source

Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk. kolosova@bionet.nsc.ru

Abstract

The biological model of prematurely aging OXYS rats is proposed for evaluation of anticataract activity of preparations. Pathological changes in the lens develop in 2-month-old OXYS rats. By the 6th month of life cataract morbidity rate attains 100%. Adrusen Zinco, Mirtilene Forte, blueberry extract, and vitamin E (Russian and from Sigma) possessing antioxidant properties and given with food decreased the number of OXYS rats with cataract. The preparation from blueberry Mirtilene Forte and blueberry extract normalized the content of lipid peroxidation products in the blood. Blueberry extract manufactured in Russia decreased the index of lipid atherogenicity that was high in OXYS rats.

PMID:: 15232631; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Supplemental Content

Save items

Related citations in PubMed

[Dietary supplementation with bilberry extract prevents macular degeneration and cataracts in senesce-accelerated OXYS rats]. [Adv Gerontol. 2005]
[Dietary supplementation with bilberry extract prevents macular degeneration and cataracts in senesce-accelerated OXYS rats].
Fursova AZh, Gesarevich OG, Gonchar AM, Trofimova NA, Kolosova NG. Adv Gerontol. 2005; 16:76-9.
[Use of mirtilene forte and adrusen zinco for correction of oxidative lesions in mitochondria in rats OXYS with inherited hyperproduction of free radicals]. [Eksp Klin Farmakol. 2001]
[Use of mirtilene forte and adrusen zinco for correction of oxidative lesions in mitochondria in rats OXYS with inherited hyperproduction of free radicals].
Shabalina IG, Shalbueva NI, Dikalova AE, Sinitsyna OI, Krysanova ZhS, Kolosova NG. Eksp Klin Farmakol. 2001 Jul-Aug; 64(4):34-6.
[Prematurely aging OXYS rats as an animal model of senile cataract in human]. [Adv Gerontol. 2003]
[Prematurely aging OXYS rats as an animal model of senile cataract in human].
Kolosova NG, Lebedev PA, Fursova AZh, Moroskova TS, Gusarevich OG. Adv Gerontol. 2003; 12:143-8.
Review Protective role of vitamin E in biological systems. [Am J Clin Nutr. 1991]
Review Protective role of vitamin E in biological systems.
Packer L. Am J Clin Nutr. 1991 Apr; 53(4 Suppl):1050S-1055S.
Review Oxidation and aging: impact on vision. [Toxicol Ind Health. 1993]
Review Oxidation and aging: impact on vision.
Taylor A, Jacques PF, Dorey CK. Toxicol Ind Health. 1993 Jan-Apr; 9(1-2):349-71.

See reviews... See all...

Cited by 1 PubMed Central article

Tryptophan and kynurenine levels in lenses of Wistar and accelerated-senescence OXYS rats. [Mol Vis. 2009]
Tryptophan and kynurenine levels in lenses of Wistar and accelerated-senescence OXYS rats.
Snytnikova OA, Kopylova LV, Chernyak EI, Morozov SV, Kolosova NG, Tsentalovich YP. Mol Vis. 2009 Dec 16; 15:2780-8. Epub 2009 Dec 16.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Comparison of antioxidants in the ability to prevent cataract in prematurely agi...
Comparison of antioxidants in the ability to prevent cataract in prematurely aging OXYS rats.
Bull Exp Biol Med. 2004 Mar ;137(3):249-51.

PubMed
Centriolar SAS-5 is required for centrosome duplication in C. elegans.
Centriolar SAS-5 is required for centrosome duplication in C. elegans.
Nat Cell Biol. 2004 Jul ;6(7):656-64.

PubMed
Systematic review of the accuracy of the ParaSight-F test in the diagnosis of Pl...
Systematic review of the accuracy of the ParaSight-F test in the diagnosis of Plasmodium falciparum malaria.
Med Sci Monit. 2004 Jul ;10(7):MT81-8. Epub 2004 Jun 29 .

PubMed
Thymoma-associated exfoliative dermatitis in cats.
Thymoma-associated exfoliative dermatitis in cats.
Vet Pathol. 2004 Jul ;41(4):429-33.

PubMed
Self-assembling protein microarrays.
Self-assembling protein microarrays.
Science. 2004 Jul 2 ;305(5680):86-90.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Comparison of antioxidants in the ability to prevent cataract in prematurely aging OXYS rats.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Cited by 1 PubMed Central article

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information