Abstract
An influenza H1N2 virus was isolated from a pig during an severe outbreak of respiratory disease in a Korean herd. The neuraminidase (NA) and PB1 genes of the H1N2 isolate were of human origin, while the hemagglutinin (HA), matrix (M), nucleoprotein (NP), and non-structural (NS) genes were of swine origin and PA and PB2 gene were of avian origin. Phylogenetic results indicate that the Korean H1N2 isolate was closely related to H1N2 viruses isolated recently from pigs in the United States.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Hemagglutinin Glycoproteins, Influenza Virus / genetics
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Hemagglutinin Glycoproteins, Influenza Virus / immunology
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Humans
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Influenza A virus / classification
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Influenza A virus / genetics*
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Influenza A virus / isolation & purification
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Korea
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Neuraminidase / genetics
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Neuraminidase / immunology
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Nucleoproteins / genetics
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Orthomyxoviridae Infections / virology*
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Phylogeny
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RNA-Dependent RNA Polymerase / genetics
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Reassortant Viruses / classification
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Reassortant Viruses / genetics*
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Reassortant Viruses / isolation & purification
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Sequence Analysis
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Sequence Homology, Nucleic Acid
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Swine / virology
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Swine Diseases / virology*
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Viral Matrix Proteins / genetics
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Viral Nonstructural Proteins / genetics
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Viral Proteins / genetics
Substances
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Hemagglutinin Glycoproteins, Influenza Virus
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Nucleoproteins
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PA protein, influenza viruses
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Viral Matrix Proteins
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Viral Nonstructural Proteins
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Viral Proteins
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influenza virus polymerase basic protein 1
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RNA-Dependent RNA Polymerase
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Neuraminidase