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J Biomech. 2004 Aug;37(8):1263-9.

Reassessment of brain elasticity for analysis of biomechanisms of hydrocephalus.

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  • 1School of Mechanical and Materials Engineering, The University of Western Australia, 35 Stirling Highway, Crawley/Perth, WA 6009, Australia.

Abstract

This paper presents results from a finite element study of the biomechanics of hydrocephalus, with special emphasis on a reassessment of the parenchyma elastic modulus. A two-dimensional finite element model of the human brain/ventricular system is developed and analysed under hydrocephalic loading conditions. It is shown that the Young's modulus of the brain parenchyma used in previous studies (3000-10000 Pa) corresponds to strain rates much higher than those present in hydrocephalic brains. Consideration of the brain's viscoelasticity leads to the derivation of a considerably lower modulus value of approximately 584 Pa.

PMID:
15212932
[PubMed - indexed for MEDLINE]
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