Integrin bidirectional signaling: a molecular view

PLoS Biol. 2004 Jun;2(6):e169. doi: 10.1371/journal.pbio.0020169. Epub 2004 Jun 15.

Abstract

Cells receive and send signals across the plasma membrane using the integrin family of receptors. What is it about their structure that can mediate their function?

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Integrins / physiology*
  • Ligands
  • Models, Biological*
  • Protein Binding / physiology
  • Protein Conformation
  • Protein Structure, Tertiary / physiology
  • Signal Transduction / physiology*

Substances

  • Integrins
  • Ligands