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1: AJNR Am J Neuroradiol. 2004 Jun-Jul;25(6):964-8.Click here to read Links
Comment in:
AJNR Am J Neuroradiol. 2004 Jun-Jul;25(6):906-7.
AJNR Am J Neuroradiol. 2005 Jan;26(1):195-7; author reply 197-8.

Acute Korsakoff syndrome following mammillothalamic tract infarction.

Yoneoka Y, Takeda N, Inoue A, Ibuchi Y, Kumagai T, Sugai T, Takeda K, Ueda K.

Department of Neurosurgery, Yamagata Prefecture Central Hospital, Yamagata, Japan.

There are limited case reports of structural lesions causing Korsakoff syndrome. This report describes acute Korsakoff syndrome following localized, bilateral infarction of the mammillothalamic tracts (MTTs). Axial T2-weighted imaging revealed the lesions at the lateral wall level of the third ventricle and diffusion-weighted imaging confirmed that the left lesion was new and the right old. Korsakoff syndrome persisted 6 months after the onset. This case suggests that bilateral MTT dysfunction can lead to Korsakoff syndrome.

PMID: 15205131 [PubMed - indexed for MEDLINE]