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Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):8942-4. Epub 2004 Jun 7.

Prediction of protein folding rates from the amino acid sequence-predicted secondary structure.

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  • 1Institute of Protein Research, Russian Academy of Sciences, Pushchino 142290, Moscow Region, Russia.

Abstract

We present a method for predicting folding rates of proteins from their amino acid sequences only, or rather, from their chain lengths and their helicity predicted from their sequences. The method achieves 82% correlation with experiment over all 64 "two-state" and "multistate" proteins (including two artificial peptides) studied up to now.

PMID:
15184682
[PubMed - indexed for MEDLINE]
PMCID:
PMC428451
Free PMC Article
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