No association between the progesterone receptor g...[Cancer Epidemiol Biomarkers Prev. 2004]

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1: Cancer Epidemiol Biomarkers Prev. 2004 Jun;13(6):1084-5. Links

No association between the progesterone receptor gene +331G/A polymorphism and breast cancer.

Feigelson HS, Rodriguez C, Jacobs EJ, Diver WR, Thun MJ, Calle EE.

Department of Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta GA 30309, USA. heather.feigelson@cancer.org

PMID: 15184270 [PubMed - indexed for MEDLINE]

GATA5 activation of the progesterone receptor gene promoter in breast cancer cells is influenced by the +331G/A polymorphism. [Cancer Res. 2006]
A functional polymorphism in the progesterone receptor gene is associated with an increase in breast cancer risk. [Cancer Res. 2003]
The progesterone receptor Val660-->Leu polymorphism and breast cancer risk. [Breast Cancer Res. 2004]
Two functionally relevant polymorphisms in the human progesterone receptor gene (+331 G/A and progins) and the predisposition for breast and/or ovarian cancer. [Gynecol Oncol. 2006]
The CYP19 gene codon 39 Trp/Arg polymorphism increases breast cancer risk in subsets of premenopausal Japanese. [Cancer Epidemiol Biomarkers Prev. 2004]
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Patient Drug Information

Progesterone (Prometrium®) Progesterone is used as a part of hormone replacement therapy in women who have passed menopause (the change of life) and have not had a hysterectomy (surgery to remove the uterus). Hormone replacement therapy usually in...

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No association between the progesterone receptor gene +331G/A polymorphism and breast cancer.

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