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    Best Pract Res Clin Obstet Gynaecol. 2004 Jun;18(3):467-76.

    Fetal scalp and cord blood lactate.

    Nordström L.

    Karolinska University Hospital, Solna, 17176 Stockholm, Sweden. lennart.nordstrom@kus.se

    Lactate measurements have been evaluated in intrapartum fetal surveillance for some 30 years. However, it was not until reliable, handheld, microvolume devices were launched during the 1990s that lactate became a clinical option. Retrospective data suggest that lactate determinations in fetal scalp blood are better than pH for predicting severe neonatal morbidity. A randomised controlled trial comparing these two measurements found lactate to be more favourable in clinical practice in terms of less sampling failure and reduced time from the decision to do a fetal scalp blood sample to the clinician receiving the result. At present, a large multicenter randomised control trial is in progress in Sweden to compare lactate and pH measurement for the clinical management of suspected fetal compromise. Main end-points in the study are metabolic acidemia or pH <7.00 in cord arterial blood at delivery. Results are likely to be available in 2-3 years time.

    PMID: 15183140 [PubMed - indexed for MEDLINE]

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