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    Nucl Med Commun. 2004 Jun;25(6):603-8.

    Characterization of the ideal candidate for knee radiosynoviorthesis treatment in patients with rheumatoid arthritis.

    Source

    Dottorato di Ricerca "Radioimmunolocalizzazione dei tumori umani" Università di Torino, Italy.

    Abstract

    OBJECTIVES:

    (1). To identify the main parameters that positively influence the outcome of knee radiosynoviorthesis (RSO) in patients with rheumatoid arthritis (RA) and (2). to determine the ideal candidate for this procedure.

    METHODS:

    We considered 80 knees (in 57 patients) that had undergone follow-up for at least 5 years and/or prosthesis implantation after RSO treatment. The parameters evaluated included age, gender, oligo-articular or polyarticular involvement, disease progression, radiological joint damage (Larsen scale), instability and/or axial deviation, body mass index (BMI), and psychological motivation for prosthesis implantation.

    RESULTS:

    Knee Larsen stage IV, presence of instability-axial deviation, disease progression, psychological motivation to the surgical replacement and BMI higher than the 85th percentile were associated with a negative outcome for RSO (prosthesis implantation).

    CONCLUSIONS:

    The ideal candidate for the RSO treatment is a patient with a low Larsen stage, no instability and/or axial deviation and a BMI below the 85th percentile. A patient's psychological motivation for the treatment should be evaluated before the RSO procedure.

    PMID:
    15167521
    [PubMed - indexed for MEDLINE]

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