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J Craniofac Surg. 2004 Mar;15(2):218-20; discussion 221.

Surgical correction of craniosynostosis in malignant osteopetrosis.

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  • 1Departments of Oral and Maxillofacial Plastic Surgery, University Hospital Tübingen, Germany. Michael.Krimmel@med.uni-tuebingen.de


In osteopetrosis, bone healing is complicated by progressive sclerosis. A 2-year-old blind boy with malignant osteopetrosis developed increased intracranial pressure secondary to craniosynostosis. Osteopetrosis had already been treated with bone marrow transplantation (BMT), and bone remodeling seemed to be restored. A craniotomy was performed. The postoperative course and bone healing were uneventful. After successful BMT, craniofacial procedures seem to be possible without a high risk for osteomyelitis.

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