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J Neurooncol. 2004 May;67(3):361-6.

Epithelioid hemangioendothelioma of the infundibular-hypothalamic region: case report and literature review.

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  • 1Department of Neurosurgery, CHRU Pontchaillou, Rennes, France. hamlat.abd@wanadoo.fr

Abstract

Epithelioid hemangioendothelioma (EHE) is an uncommon vascular neoplasm. Its intracranial occurrence is rare, and the literature review revealed only 23 cases (14 adults and 9 children). To our knowledge, this is the first case of EHE arising in the infundibular-hypothalamic region. A 53-year-old man presented with headaches and loss of libido. Magnetic resonance imaging revealed a supra-sellar mass, which homogeneously absorbed the contrast agent. A trans-sphenoidal craniotomy and a biopsy were performed. Adjuvant radiotherapy was administered due to intolerance to interferon. Epithelioid hemangioendothelioma is a hemorrhagic tumor. Total resection is mandatory where possible, otherwise radiotherapy seems necessary. The prognosis of intracranial location has not yet been well defined, despite the favorable outcome noted in the majority of cases.

PMID:
15164993
[PubMed - indexed for MEDLINE]
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