Methotrexate-induced leukoencephalopathy reversed by aminophylline and high-dose folinic acid

Acta Haematol. 2004;111(4):230-2. doi: 10.1159/000077573.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aminophylline / administration & dosage*
  • Aminophylline / therapeutic use
  • Brain Diseases / chemically induced*
  • Brain Diseases / diagnosis
  • Brain Diseases / drug therapy
  • Female
  • Humans
  • Leucovorin / administration & dosage*
  • Leucovorin / therapeutic use
  • Magnetic Resonance Imaging
  • Methotrexate / adverse effects*
  • Neurotoxicity Syndromes / diagnosis
  • Neurotoxicity Syndromes / drug therapy
  • Neurotoxicity Syndromes / etiology*
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / complications
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Treatment Outcome

Substances

  • Aminophylline
  • Leucovorin
  • Methotrexate