Send to

Choose Destination
See comment in PubMed Commons below
Curr Opin Cell Biol. 2004 Jun;16(3):279-84.

The ever-increasing complexities of the exon junction complex.

Author information

  • 1Howard Hughes Medical Institute, Department of Biochemistry, MS009, Brandeis University, 415 South Street, Waltham, Massachusetts 02454, USA.


Over the past decade many studies have revealed a complex web of interconnections between the numerous steps required for eukaryotic gene expression. One set of interconnections link nuclear pre-mRNA splicing and the subsequent metabolism of the spliced mRNAs. It is now apparent that the means of connection is a set of proteins, collectively called the exon junction complex, which are deposited as a consequence of splicing upstream of mRNA exon-exon junctions.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk