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Med J Aust. 2004 May 17;180(10):508-11.

Association between diabetes and coronary heart disease in Aboriginal people: are women disadvantaged?

Author information

  • 1Department of Medicine, School of Medicine - Central Clinical Division, University of Queensland, F4, Block 6, Royal Brisbane Hospital, Herston. zwang@ccs.uq.edu.au

Abstract

OBJECTIVES:

To determine the incidence rate of coronary heart disease (CHD) in Australian Aboriginal people with type 2 diabetes, and to compare the impact of diabetes on CHD risk in Aboriginal women and men.

DESIGN:

Cohort study.

SETTING:

A remote Aboriginal community in the Northern Territory.

PARTICIPANTS:

889 Aboriginal people aged 20-74 years followed up to 31 May 2003 after baseline examination in 1992-1995.

MAIN OUTCOME MEASURES:

Incidence rates of CHD (estimated for 123 participants with diabetes at baseline and 701 "non-diabetes" participants); rate ratios for diabetes risk (95% CI), with "non-diabetes" participants as the reference group.

RESULTS:

Participants with diabetes at baseline had a higher rate of CHD (37.5 per 1000 person-years) than those without diabetes (7.3 per 1000 person-years). Adjustment for multiple CHD risk factors, such as age, smoking, alcohol consumption, systolic blood pressure, body mass index, high-density lipoprotein cholesterol and total cholesterol levels, resulted in a CHD rate ratio for women of 3.7 (95% CI, 1.6-8.9) (comparing women with diabetes with those without) and a CHD rate ratio for men of 1.4 (95% CI, 0.4-4.1) (comparing men with diabetes with those without).

CONCLUSIONS:

Aboriginal women with diabetes experienced a significantly higher risk of CHD than women without diabetes. Although the difference was not statistically significant, women with diabetes had a higher CHD risk than men with diabetes.

PMID:
15139827
[PubMed - indexed for MEDLINE]
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